Peptide Atlas · Excipient

Glycerol

Glycerol is a cosolvent that stabilizes proteins in solution: seven proteins studied in glycerol-water mixtures were preferentially hydrated, which minimizes glycerol contact and favours the native structure.

preclinical

provisional
PubChem 753
2 citations
0 discussions
0 followers
Glycerol (vegetable-derived, USP grade)

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- preclinical
  Claim: Mechanisms of protein stabilization and aggregation prevention by glycerol standing
- resolved
Mechanisms of protein stabilization and prevention of protein aggregation by glycerol.
Vagenende V, Yap MG, Trout BL
pmid 19817484
- preclinical
  Claim: Protein stabilization by glycerol through preferential hydration standing
- resolved
Mechanism of protein stabilization by glycerol: preferential hydration in glycerol-water mixtures.
Gekko K, Timasheff SN
pmid 7295639

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Negative findings

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