Peptide Atlas · Buffer system

Histidine buffer

Histidine buffers are widely used in freeze-dried monoclonal antibody formulations, often as histidine-HCl.

preclinical

provisional
2 citations
0 discussions
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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- preclinical
  Claim: Photosensitizers in histidine buffer standing
- resolved
Photosensitizers form in histidine buffer and mediate the photodegradation of a monoclonal antibody.
Stroop SD, Conca DM, Lundgard RP, Renz ME, Peabody LM, Leigh SD
pmid 21786276
- preclinical
  Claim: Histidine buffers in freeze-dried antibody formulations standing
- resolved
A novel histidine-acetate buffer for freeze-dried monoclonal antibody formulations.
Lv JY, Gao H, Xie HF, Jin MJ, Di B, Xu J, Fang WJ
pmid 41308842

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