Peptide Atlas · Vitamin

Hydroxocobalamin

Hydroxocobalamin is a cyanide antidote: among 69 smoke-inhalation victims with suspected cyanide poisoning given 5 g intravenously, 72% survived, 67% of those with confirmed poisoning, with no serious adverse events attributed to it.

emerging

provisional
PubChem 44475014
2 citations
0 discussions
0 followers
Hydroxocobalamin acetate (salt form)
Hydroxycobalamin
OH-Cbl
Vitamin B12a

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: Hydroxocobalamin for cyanide poisoning in smoke inhalation (prospective case series) standing
- resolved
Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation.
Borron SW, Baud FJ, Barriot P, Imbert M, Bismuth C
pmid 17481777
- emerging
  Claim: Hydroxocobalamin safety and cyanide lowering in healthy smokers standing
- resolved
Hydroxocobalamin as a cyanide antidote: safety, efficacy and pharmacokinetics in heavily smoking normal volunteers.
Forsyth JC, Mueller PD, Becker CE, Osterloh J, Benowitz NL, Rumack BH, Hall AH
pmid 8492341

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Negative findings

failure is information

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