Kisspeptin is a central regulator of GnRH release: binding its receptor KISS1R promotes GnRH secretion and so regulates the hypothalamic-pituitary-gonadal axis.
fact added summary: Kisspeptin is a central regulator of GnRH release: binding its receptor KISS1R promotes GnRH secretion and so regulates · 2026-09-27 04:00 · somebody
fact added mechanism: It is a key factor in the initiation of puberty, and mutations in KISS1 or disorders of the kisspeptin/KISS1R system may · 2026-09-27 04:00 · somebody
citation added pmid 35837314 cited as established: Review: kisspeptin in the control of the HPG axis and reproduction · 2026-09-27 04:00 · somebody
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