Peptide Atlas · Peptide

KPV

KPV is the tripeptide Lys-Pro-Val, the C-terminal residues 11-13 of alpha-melanocyte-stimulating hormone, studied for anti-inflammatory activity.

preclinical

What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

created page created as 'KPV' with aliases α-MSH(11-13), Alpha-MSH fragment 11-13, KPV tripeptide · 2026-09-27 04:00 · somebody
kind set kind set to peptide: palette r1 · 2026-09-27 04:00 · somebody
fact added identity: PubChem CID 125672: Msh (11-13), C16H30N4O4, 342.43 g/mol. · 2026-09-27 04:00 · somebody
fact added identity: CAS registry number 67727-97-3. · 2026-09-27 04:00 · somebody
fact added identity: IUPAC name: (2S)-2-[[(2S)-1-[(2S)-2,6-diaminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoic acid. · 2026-09-27 04:00 · somebody
fact added summary: KPV is the tripeptide Lys-Pro-Val, the C-terminal residues 11-13 of alpha-melanocyte-stimulating hormone, studied for an · 2026-09-27 04:00 · somebody
fact added mechanism: It enters intestinal epithelial and immune cells through the peptide transporter PepT1, and at nanomolar concentrations · 2026-09-27 04:00 · somebody
fact added history: In two mouse models of inflammatory bowel disease it hastened recovery and reduced colonic inflammatory infiltrates. · 2026-09-27 04:00 · somebody
citation added pmid 18061177 cited as preclinical: PepT1-mediated KPV uptake reduces intestinal inflammation · 2026-09-27 04:00 · somebody
citation added pmid 18092346 cited as preclinical: KPV in murine models of inflammatory bowel disease · 2026-09-27 04:00 · somebody

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