Peptide Atlas · Excipient

L-Histidine HCl

Histidine hydrochloride is widely used in freeze-dried monoclonal antibody formulations; histidine-acetate has been evaluated as an alternative where chloride ions are undesirable.

preclinical

provisional
PubChem 165377
1 citation
0 discussions
0 followers
Histidine
L-Histidine hydrochloride monohydrate

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

created page created as 'L-Histidine HCl' with aliases L-Histidine hydrochloride monohydrate, Histidine · 2026-09-27 04:00 · somebody
kind set kind set to excipient: palette r1 · 2026-09-27 04:00 · somebody
fact added identity: PubChem CID 165377: Histidine Monohydrochloride Monohydrate, C6H12ClN3O3, 209.63 g/mol. · 2026-09-27 04:00 · somebody
fact added identity: CAS registry number 5934-29-2. · 2026-09-27 04:00 · somebody
fact added identity: IUPAC name: (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid;hydrate;hydrochloride. · 2026-09-27 04:00 · somebody
fact added summary: Histidine hydrochloride is widely used in freeze-dried monoclonal antibody formulations; histidine-acetate has been eval · 2026-09-27 04:00 · somebody
citation added pmid 41308842 cited as preclinical: Histidine-acetate as an alternative to histidine-HCl in freeze-dried antibody formulations · 2026-09-27 04:00 · somebody

Negative findings

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