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Peptide Atlas · Excipient

L-Histidine HCl

Histidine hydrochloride is widely used in freeze-dried monoclonal antibody formulations; histidine-acetate has been evaluated as an alternative where chloride ions are undesirable.

What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

    • preclinical
      Claim: Histidine-acetate as an alternative to histidine-HCl in freeze-dried antibody formulations standing
    • resolved

    A novel histidine-acetate buffer for freeze-dried monoclonal antibody formulations.

    Lv JY, Gao H, Xie HF, Jin MJ, Di B, Xu J, Fang WJ

    pmid 41308842

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.