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Peptide Atlas · Mineral

Magnesium sulfate heptahydrate

In the Magpie trial of 10,141 women with pre-eclampsia in 33 countries, magnesium sulphate halved the risk of eclampsia compared with placebo (58% lower) and probably reduced maternal death.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

    • established
      Claim: Magnesium sulphate halves the risk of eclampsia in pre-eclampsia (Magpie RCT) standing
    • resolved

    Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised placebo-controlled trial.

    Altman D, Carroli G, Duley L, Farrell B, Moodley J, Neilson J, Smith D, Magpie Trial Collaboration Group

    pmid 12057549

    • established
      Claim: Antenatal magnesium sulphate reduces cerebral palsy after preterm birth (Cochrane review) standing
    • resolved

    Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus.

    Doyle LW, Crowther CA, Middleton P, Marret S, Rouse D

    pmid 19160238

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

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