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Peptide Atlas · Peptide

Melanotan II

Melanotan II is a lactam-bridged cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone, Ac-Nle4-Asp5-His6-D-Phe7-Arg8-Trp9-Lys10 alpha-MSH(4-10)-NH2, with superpotent melanotropic activity in vitro.

What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

  • created page created as 'Melanotan II' · 2026-09-27 04:00 · somebody
  • kind set kind set to peptide: palette r1 · 2026-09-27 04:00 · somebody
  • fact added identity: PubChem CID 92432: melanotan-II, C50H69N15O9, 1024.2 g/mol. · 2026-09-27 04:00 · somebody
  • fact added identity: CAS registry number 121062-08-6. · 2026-09-27 04:00 · somebody
  • fact added identity: IUPAC name: (3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-1 · 2026-09-27 04:00 · somebody
  • fact added summary: Melanotan II is a lactam-bridged cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone, Ac-Nle4-Asp5-His6 · 2026-09-27 04:00 · somebody
  • fact added history: In a pilot phase I study in three men it increased skin pigmentation, and spontaneous erections and a stretching and yaw · 2026-09-27 04:00 · somebody
  • fact added history: In a double-blind crossover study of 20 men with erectile dysfunction, Melanotan II, a non-selective melanocortin recept · 2026-09-27 04:00 · somebody
  • citation added pmid 8637402 cited as emerging: Pilot phase I study of melanotan II · 2026-09-27 04:00 · somebody
  • citation added pmid 11035391 cited as emerging: Melanotan II in men with erectile dysfunction · 2026-09-27 04:00 · somebody

Negative findings

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