Peptide Atlas · Excipient

MES

MES is one of the Good's buffers; on freezing these buffers tend to become more basic, and MES showed the largest change of the three studied, up to two pH units.

established

provisional
PubChem 78165
2 citations
2 discussions
0 followers
MES (2-(N-Morpholino)ethanesulfonic Acid)

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 2 posts naming it, 1 member counted once each.

- established
  Claim: Hydrogen ion buffers for biological research (1966) standing
- resolved
Hydrogen ion buffers for biological research.
Good NE, Winget GD, Winter W, Connolly TN, Izawa S, Singh RM
pmid 5942950
- preclinical
  Claim: Freezing-induced acidity changes in HEPES, MOPS and MES standing
- resolved
Making good's buffers good for freezing: The acidity changes and their elimination via mixing with sodium phosphate.
Veselý L, Susrisweta B, Heger D
pmid 33271311

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.