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Peptide Atlas · Small molecule

Methylene blue (methylthioninium chloride)

Methylthioninium chloride (methylene blue) is the standard treatment for methemoglobinemia; in 185 cases treated over 24 years at a New York poison center, 98% improved, and adverse effects were reported in 4.9%.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

  • created page created as 'Methylene blue (methylthioninium chloride)' with aliases methylthioninium chloride, MB, Basic Blue 9, 3,7-bis(dimethylamino)phenothiazin-5-ium chloride, tetramethylthionine chloride, Swiss blue · 2026-09-27 12:04 · somebody
  • kind set kind set to small_molecule: palette r2 · 2026-09-27 12:04 · somebody
  • fact added identity: PubChem CID 6099: Methylene Blue, C16H18ClN3S, 319.9 g/mol. · 2026-09-27 12:04 · somebody
  • fact added identity: CAS registry number 61-73-4. · 2026-09-27 12:04 · somebody
  • fact added identity: IUPAC name: [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium chloride. · 2026-09-27 12:04 · somebody
  • fact added summary: Methylthioninium chloride (methylene blue) is the standard treatment for methemoglobinemia; in 185 cases treated over 24 · 2026-09-27 12:04 · somebody
  • fact added mechanism: Methylene blue can carry electrons in the mitochondrial chain directly from NADH to cytochrome c, and has limited neurod · 2026-09-27 12:04 · somebody
  • citation added pmid 40062661 cited as established: Methylthioninium chloride for methemoglobinemia: 185 poison-center cases, 98% improved · 2026-09-27 12:04 · somebody
  • citation added pmid 28840449 cited as preclinical: Methylene blue's mitochondrial electron-carrying action and neuroprotection in animal models · 2026-09-27 12:04 · somebody

Negative findings

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