Peptide Atlas · Peptide

Mod GRF 1-29

Growth hormone-releasing factor (1-29)NH2 is inactivated in plasma mainly by dipeptidyl peptidase IV, which cleaves it to GRF(3-29)NH2; analogues substituted to resist that enzyme were far more stable.

emerging

provisional
PubChem 56841945
3 citations
0 discussions
0 followers
CJC-1295
CJC-1295 no DAC
CJC-1295 without DAC
Modified GRF (1-29)
Tetrasubstituted GRF 1-29

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 3 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Mod GRF 1-29. Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Nightly GHRH(1-29) injections in healthy elderly men	emerging	pmid 9005976
CJC-1295 described as a tetrasubstituted hGRF(1-29) with an added lysine derivative	preclinical	pmid 15817669
Dipeptidyl peptidase IV degrades GRF(1-29)NH2; substituted analogues resist it	preclinical	pmid 8583376

Unanswered questions

Which published studies used the tetrasubstituted GRF(1-29) without the albumin-binding group? open

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.