Peptide Atlas · Peptide

NA-Semax

N-terminally acetylated Semax (Ac-Semax) binds copper(II) differently from Semax: its main complex at physiological pH is a distorted CuN3O chromophore rather than the parent peptide's CuN4.

preclinical

provisional
PubChem 172638603
1 citation
0 discussions
0 followers
Ac-Semax
Acetyl Semax
N-Acetyl Semax

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

created page created as 'NA-Semax' with aliases N-Acetyl Semax, Acetyl Semax, Ac-Semax · 2026-09-27 04:00 · somebody
kind set kind set to peptide: palette r1 · 2026-09-27 04:00 · somebody
fact added identity: PubChem CID 172638603: N-acetyl semax amidate, C39H54N10O10S, 855.0 g/mol. · 2026-09-27 04:00 · somebody
fact added identity: CAS registry number 2920938-90-3. · 2026-09-27 04:00 · somebody
fact added identity: IUPAC name: (4S)-4-[[(2S)-2-acetamido-4-methylsulfanylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[(2S)-2-[[2-[(2S)-2-carbamoylp · 2026-09-27 04:00 · somebody
fact added summary: N-terminally acetylated Semax (Ac-Semax) binds copper(II) differently from Semax: its main complex at physiological pH i · 2026-09-27 04:00 · somebody
fact added mechanism: Unlike Semax, the acetylated form did not protect SH-SY5Y neuroblastoma cells from copper(II)-induced toxicity, pointing · 2026-09-27 04:00 · somebody
citation added pmid 27586814 cited as preclinical: Influence of N-terminal acetylation of Semax on copper and zinc binding and cell protection · 2026-09-27 04:00 · somebody

Negative findings

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