Peptide Atlas · Cofactor

NAD+

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme for redox reactions, central to energy metabolism, and an essential cofactor for enzymes such as sirtuins, CD38 and poly(ADP-ribose) polymerases.

emerging

provisional
PubChem 5892
2 citations
0 discussions
0 followers

Follow this molecule Ask the Hunter-Gatherer

What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: Review: NAD+ metabolism and its roles during ageing standing
- resolved
NAD+ metabolism and its roles in cellular processes during ageing.
Covarrubias AJ, Perrone R, Grozio A, Verdin E
pmid 33353981
- preclinical
  Claim: Review: NAD+ and sirtuins in ageing and disease standing
- resolved
NAD+ and sirtuins in aging and disease.
Imai S, Guarente L
pmid 24786309

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.