Peptide Atlas · Peptide

PTD-DBM

PTD-DBM (protein transduction domain fused to a Dishevelled-binding motif) is a competitor peptide that blocks the interaction of CXXC5 with Dishevelled, a negative feedback brake on Wnt/beta-catenin signalling.

preclinical

provisional
1 citation
0 discussions
0 followers
CXXC5 inhibitor peptide
Protein Transduction Domain-Dishevelled Binding Motif
TAT-CTNNSRSS

Follow this molecule Ask the Hunter-Gatherer

What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

- preclinical
  Claim: CXXC5 negatively regulates wound healing; PTD-DBM blocks the CXXC5-Dishevelled interaction standing
- resolved
The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing.
Lee SH, Kim MY, Kim HY, Lee YM, Kim H, Nam KA, Roh MR, Min do S, Chung KY, Choi KY
pmid 26056233

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.