Peptide Atlas · Cofactor

Pyridoxal 5'-phosphate

Pyridoxal 5'-phosphate (PLP) is the active coenzyme form of vitamin B6; PLP-dependent enzymes catalyze an unrivalled diversity of reactions.

established

provisional
PubChem 1051
2 citations
0 discussions
0 followers
Active B6
P5P
PLP
Pyridoxal phosphate

Follow this molecule Ask the Hunter-Gatherer

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Pyridoxal 5'-phosphate. Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Systematic review of pyridoxal-5'-phosphate treatment in PNPO deficiency	emerging	pmid 40751583
Review of pyridoxal phosphate-dependent enzymes	established	pmid 15189147

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.