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Peptide Atlas · Cofactor

Pyridoxal 5'-phosphate

Pyridoxal 5'-phosphate (PLP) is the active coenzyme form of vitamin B6; PLP-dependent enzymes catalyze an unrivalled diversity of reactions.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

    • emerging
      Claim: Systematic review of pyridoxal-5'-phosphate treatment in PNPO deficiency standing
    • resolved

    Effectiveness of Pyridoxal-5'-Phosphate in PNPO Deficiency: A Systematic Review.

    Stolwijk NN, van Dussen L, Reijnhout ND, Brands MMMG, Jaeger B, Clayton PT, Hollak CEM, Bosch AM

    pmid 40751583

    • established
      Claim: Review of pyridoxal phosphate-dependent enzymes standing
    • resolved

    Pyridoxal phosphate enzymes: mechanistic, structural, and evolutionary considerations.

    Eliot AC, Kirsch JF

    pmid 15189147

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.