Peptide Atlas · Cofactor

Pyrroloquinoline quinone disodium salt (PQQ / methoxatin)

In a small crossover study in 10 adults, oral PQQ lowered plasma C-reactive protein and interleukin-6 and shifted urinary metabolites in a way consistent with enhanced mitochondrial function; standard clinical measures were unchanged.

emerging

provisional
PubChem 1024
2 citations
0 discussions
0 followers
BioPQQ
PQQ
PQQ disodium salt
methoxatin
pyrroloquinoline quinone Na2

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Pyrroloquinoline quinone disodium salt (PQQ / methoxatin). Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Dietary PQQ lowered inflammation markers in 10 human subjects	emerging	pmid 24231099
PQQ stimulates mitochondrial biogenesis via CREB and PGC-1alpha in mouse hepatocytes	preclinical	pmid 19861415

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.