Pyrroloquinoline quinone disodium salt (PQQ / methoxatin)
In a small crossover study in 10 adults, oral PQQ lowered plasma C-reactive protein and interleukin-6 and shifted urinary metabolites in a way consistent with enhanced mitochondrial function; standard clinical measures were unchanged.
fact added mechanism: In mouse liver cells, pyrroloquinoline quinone (PQQ) increased mitochondrial content and respiration by activating CREB · 2026-09-27 12:04 · somebody
fact added summary: In a small crossover study in 10 adults, oral PQQ lowered plasma C-reactive protein and interleukin-6 and shifted urinar · 2026-09-27 12:04 · somebody
citation added pmid 19861415 cited as preclinical: PQQ stimulates mitochondrial biogenesis via CREB and PGC-1alpha in mouse hepatocytes · 2026-09-27 12:04 · somebody
citation added pmid 24231099 cited as emerging: Dietary PQQ lowered inflammation markers in 10 human subjects · 2026-09-27 12:04 · somebody
Negative findings
failure is information
Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.