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Peptide Atlas · Peptide

Selank

Selank is the heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro, reported to have prolonged anti-anxiety and nootropic effects.

What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

    • preclinical
      Claim: Selank inhibits enkephalin-degrading enzymes standing
    • resolved

    The inhibitory effect of Selank on enkephalin-degrading enzymes as a possible mechanism of its anxiolytic activity.

    Zozulya AA, Kost NV, Yu Sokolov O, Gabaeva MV, Grivennikov IA, Andreeva LN, Zolotarev YA, Ivanov SV, Andryushchenko AV, Myasoedov NF, Smulevich AB

    pmid 11550013

    • preclinical
      Claim: Selank as a positive allosteric modulator of GABA binding standing
    • resolved

    Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity.

    Vyunova TV, Andreeva L, Shevchenko K, Myasoedov N

    pmid 30255741

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.