Semax is the heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro, an analogue of the adrenocorticotropin fragment (4-10), reported after intranasal application to affect learning and to be neuroprotective.
fact added summary: Semax is the heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro, an analogue of the adrenocorticotropin fragment (4-10), reported · 2026-09-27 04:00 · somebody
fact added mechanism: A single application in rats raised hippocampal BDNF protein up to 1.4-fold and trkB phosphorylation 1.6-fold. · 2026-09-27 04:00 · somebody
fact added history: A 1997 review of fifteen years of its development describes it as one of the rare regulatory-peptide analogues to pass f · 2026-09-27 04:00 · somebody
citation added pmid 16996037 cited as preclinical: Semax regulates BDNF and trkB in the rat hippocampus · 2026-09-27 04:00 · somebody
citation added pmid 9173745 cited as emerging: Fifteen years of Semax design and study (Russian-language review) · 2026-09-27 04:00 · somebody
Negative findings
failure is information
Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.