Peptide Atlas · Peptide

Semax

Semax is the heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro, an analogue of the adrenocorticotropin fragment (4-10), reported after intranasal application to affect learning and to be neuroprotective.

emerging

provisional
7 aa
PubChem 9811102
2 citations
0 discussions
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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: Fifteen years of Semax design and study (Russian-language review) standing
- resolved
[A nootropic adrenocorticotropin analog 4-10-semax (l5 years experience in its design and study)].
Asmarin IP, Nezavibat'ko VN, Miasoedov NF, Kamenskiĭ AA, Grivennikov IA, Ponomareva-Stepnaia MA, Andreeva LA, Kaplan AIa, Koshelev VB, Riasina TV
pmid 9173745
- preclinical
  Claim: Semax regulates BDNF and trkB in the rat hippocampus standing
- resolved
Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus.
Dolotov OV, Karpenko EA, Inozemtseva LS, Seredenina TS, Levitskaya NG, Rozyczka J, Dubynina EV, Novosadova EV, Andreeva LA, Alfeeva LY, Kamensky AA, Grivennikov IA, Myasoedov NF, Engele J
pmid 16996037

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Negative findings

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