Peptide Atlas · Peptide

Setmelanotide

Setmelanotide is a melanocortin-4 receptor agonist, first approved in the United States for chronic weight management in patients aged 6 and older with obesity caused by POMC, PCSK1 or leptin receptor deficiency.

established

provisional
PubChem 11993702
1 citation
0 discussions
0 followers
BIM-22493
Imcivree
MC4R agonist
RM-493
Setmelanotide acetate

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

- established
  Claim: Setmelanotide: first approval for obesity due to POMC, PCSK1 or LEPR deficiency standing
- resolved
Setmelanotide: First Approval.
Markham A
pmid 33638809

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

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