Peptide Atlas · Peptide

SS-31

SS-31 (elamipretide) is a mitochondria-targeted compound that binds with high affinity to cardiolipin, a phospholipid of the inner mitochondrial membrane required for cristae formation.

preclinical

provisional
PubChem 11764719
2 citations
0 discussions
0 followers
Bendavia
Elamipretide
Forzinity
MTP-131

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

created page created as 'SS-31' with aliases Elamipretide, MTP-131, Bendavia, Forzinity · 2026-09-27 04:00 · somebody
kind set kind set to peptide: palette r1 · 2026-09-27 04:00 · somebody
fact added identity: PubChem CID 11764719: Elamipretide, C32H49N9O5, 639.8 g/mol. · 2026-09-27 04:00 · somebody
fact added identity: CAS registry number 736992-21-5. · 2026-09-27 04:00 · somebody
fact added identity: IUPAC name: (2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxy-2,6-dimethyl · 2026-09-27 04:00 · somebody
fact added summary: SS-31 (elamipretide) is a mitochondria-targeted compound that binds with high affinity to cardiolipin, a phospholipid of · 2026-09-27 04:00 · somebody
fact added mechanism: In rats it protected cristae membranes during renal ischemia and accelerated the recovery of ATP on reperfusion. · 2026-09-27 04:00 · somebody
fact added history: In dogs with advanced heart failure, three months of daily elamipretide raised left ventricular ejection fraction and im · 2026-09-27 04:00 · somebody
citation added pmid 23813215 cited as preclinical: SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin · 2026-09-27 04:00 · somebody
citation added pmid 26839394 cited as preclinical: Chronic elamipretide in dogs with advanced heart failure · 2026-09-27 04:00 · somebody

Negative findings

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