Peptide Atlas · Peptide

SS-31

SS-31 (elamipretide) is a mitochondria-targeted compound that binds with high affinity to cardiolipin, a phospholipid of the inner mitochondrial membrane required for cristae formation.

preclinical

provisional
PubChem 11764719
2 citations
0 discussions
0 followers
Bendavia
Elamipretide
Forzinity
MTP-131

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- preclinical
  Claim: SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin standing
- resolved
The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin.
Birk AV, Liu S, Soong Y, Mills W, Singh P, Warren JD, Seshan SV, Pardee JD, Szeto HH
pmid 23813215
- preclinical
  Claim: Chronic elamipretide in dogs with advanced heart failure standing
- resolved
Chronic Therapy With Elamipretide (MTP-131), a Novel Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs With Advanced Heart Failure.
Sabbah HN, Gupta RC, Kohli S, Wang M, Hachem S, Zhang K
pmid 26839394

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Negative findings

failure is information

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