Peptide Atlas · Small molecule

Taurine

Taurine is one of the most abundant amino acids in the body but is not built into proteins; it acts as an osmolyte, forms bile salts and modulates intracellular calcium, and its deficiency is associated with cardiomyopathy and retinal damage.

established

provisional
PubChem 1123
2 citations
0 discussions
0 followers
2-aminoethanesulfonic acid

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- established
  Claim: Taurine's physiological roles and the consequences of its deficiency standing
- resolved
Review: taurine: a "very essential" amino acid.
Ripps H, Shen W
pmid 23170060
- preclinical
  Claim: Taurine decline with age; supplementation extended health span in mice and monkeys standing
- resolved
Taurine deficiency as a driver of aging.
Singh P, Gollapalli K, Mangiola S, Schranner D, Yusuf MA, Chamoli M, Shi SL, Lopes Bastos B, Nair T, Riermeier A, Vayndorf EM, Wu JZ, Nilakhe A, Nguyen CQ, Muir M, Kiflezghi MG, Foulger A, Junker A, Devine J, Sharan K, Chinta SJ, Rajput S, Rane A, Baumert P, Schönfelder M, Iavarone F, di Lorenzo G, Kumari S, Gupta A, Sarkar R, Khyriem C, Chawla AS, Sharma A, Sarper N, Chattopadhyay N, Biswal BK, Settembre C, Nagarajan P, Targoff KL, Picard M, Gupta S, Velagapudi V, Papenfuss AT, Kaya A, Ferreira MG, Kennedy BK, Andersen JK, Lithgow GJ, Ali AM, Mukhopadhyay A, Palotie A, Kastenmüller G, Kaeberlein M, Wackerhage H, Pal B, Yadav VK
pmid 37289866

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

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