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Peptide Atlas · Small molecule

Taurine

Taurine is one of the most abundant amino acids in the body but is not built into proteins; it acts as an osmolyte, forms bile salts and modulates intracellular calcium, and its deficiency is associated with cardiomyopathy and retinal damage.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Summary

Taurine is one of the most abundant amino acids in the body but is not built into proteins; it acts as an osmolyte, forms bile salts and modulates intracellular calcium, and its deficiency is associated with cardiomyopathy and retinal damage. · pmid:23170060

Circulating taurine fell with age in mice, monkeys and humans, and taurine supplementation lengthened health span in mice and monkeys and life span in mice; the authors called for trials in humans. · pmid:37289866

Identity

PubChem CID 1123: Taurine, C2H7NO3S, 125.15 g/mol. · pubchem:1123

CAS registry number 107-35-7. · pubchem:1123

IUPAC name: 2-aminoethanesulfonic acid. · pubchem:1123


Where the evidence actually sits

Established50%
Preclinical only50%

Proportion of the 2 claims about Taurine standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.


Living evidence history

Review: taurine: a "very essential" amino acid. (2012) · establishedTaurine deficiency as a driver of aging. (2023) · preclinical20122023

2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.


Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Taurine yet.


Dose evidence, rung by rung

A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.

  1. Approved-label dose · a resolved regulatory document names a labelled dose

    nothing resolved on this rung

  2. Studied human doses · resolved human studies at the established tier
    • Review: taurine: a "very essential" amino acid. · pmid 23170060 · 2012
  3. Observational evidence · resolved human data at the emerging tier: thin, or contested

    nothing resolved on this rung

  4. Community-reported protocols · protocol propositions from distinct members, counted once per human

    nothing resolved on this rung

  5. Preclinical evidence · resolved animal, cell or mechanistic work
    • Taurine deficiency as a driver of aging. · pmid 37289866 · 2023

2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.