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Peptide Atlas · Vitamin

Thiamine hydrochloride

Thiamine is an essential micronutrient central to energy metabolism; populations relying on milled or washed staple grains are at risk of deficiency, which contributes to infant mortality through infantile beriberi.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

    • emerging
      Claim: Vitamin C, thiamine and hydrocortisone did not improve sepsis outcomes (VICTAS, stopped early) standing
    • resolved

    Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial.

    Sevransky JE, Rothman RE, Hager DN, Bernard GR, Brown SM, Buchman TG, Busse LW, Coopersmith CM, DeWilde C, Ely EW, Eyzaguirre LM, Fowler AA, Gaieski DF, Gong MN, Hall A, Hinson JS, Hooper MH, Kelen GD, Khan A, Levine MA, Lewis RJ, Lindsell CJ, Marlin JS, McGlothlin A, Moore BL, Nugent KL, Nwosu S, Polito CC, Rice TW, Ricketts EP, Rudolph CC, Sanfilippo F, Viele K, Martin GS, Wright DW, VICTAS Investigators

    pmid 33620405

    • established
      Claim: Thiamine deficiency disorders: diagnosis, prevalence and control standing
    • resolved

    Thiamine deficiency disorders: diagnosis, prevalence, and a roadmap for global control programs.

    Whitfield KC, Bourassa MW, Adamolekun B, Bergeron G, Bettendorff L, Brown KH, Cox L, Fattal-Valevski A, Fischer PR, Frank EL, Hiffler L, Hlaing LM, Jefferds ME, Kapner H, Kounnavong S, Mousavi MPS, Roth DE, Tsaloglou MN, Wieringa F, Combs GF

    pmid 30151974

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

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