Peptide Atlas · Peptide

Thymogen (Glu-Trp, EW)

preclinical

What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

created page created as 'Thymogen (Glu-Trp, EW)' with aliases Thymagen, EW dipeptide, alpha-glutamyl-tryptophan · 2026-09-27 12:04 · somebody
kind set kind set to peptide: palette r2 · 2026-09-27 12:04 · somebody
fact added identity: PubChem CID 100094: Thymogen, C16H19N3O5, 333.34 g/mol. · 2026-09-27 12:04 · somebody
fact added identity: CAS registry number 38101-59-6, 122933-59-9. · 2026-09-27 12:04 · somebody
fact added identity: IUPAC name: (4S)-4-amino-5-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid. · 2026-09-27 12:04 · somebody
fact added classification: Thymogen is the dipeptide L-Glu-L-Trp, an immunostimulant; its enantiomer D-Glu(D-Trp), thymodepressin, acts as an immun · 2026-09-27 12:04 · somebody
fact added mechanism: In an in vitro model of inflammation, alpha-glutamyl-tryptophan reduced TNF-alpha-induced IL-1-alpha production in endot · 2026-09-27 12:04 · somebody
citation added pmid 38732260 cited as preclinical: Thymogen (L-Glu-L-Trp) and thymodepressin (D-Glu(D-Trp)) as enantiomeric drugs with opposite actions · 2026-09-27 12:04 · somebody
citation added pmid 37131521 cited as preclinical: alpha-Glu-Trp modulates cytokine secretion and ICAM-1 in vitro · 2026-09-27 12:04 · somebody

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