Peptide Atlas · Protein

Thymopoietin

Thymopoietin II, isolated from bovine thymus as a hormone that drives T-cell differentiation, is a single polypeptide chain of 49 amino acids with a mass of 5,562 daltons.

emerging

provisional
3 citations
0 discussions
0 followers
TMPO-derived thymic polypeptide
TP
splice variants α/β/γ
thymopoietin II

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 3 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Thymopoietin. Tier reflects study design, not enthusiasm.
Claim	Tier	Source
The TMPO (LAP2) gene carries a LAP2-alpha variant in a familial dilated cardiomyopathy pedigree	emerging	pmid 16247757
Amino acid sequence of bovine thymopoietin II (49 residues)	preclinical	pmid 1171728
A synthetic thymopoietin 32-36 pentapeptide carries the hormone's T-cell differentiating activity	preclinical	pmid 451537

Unanswered questions

Is the thymic hormone described in the 1970s the same molecule as the TMPO gene's lamina-associated polypeptide 2, or do they only share a name? open

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.