Peptide Atlas · Protein

Thymopoietin

Thymopoietin II, isolated from bovine thymus as a hormone that drives T-cell differentiation, is a single polypeptide chain of 49 amino acids with a mass of 5,562 daltons.

emerging

provisional
3 citations
0 discussions
0 followers
TMPO-derived thymic polypeptide
TP
splice variants α/β/γ
thymopoietin II

Follow this molecule Ask the Hunter-Gatherer

What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 3 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: The TMPO (LAP2) gene carries a LAP2-alpha variant in a familial dilated cardiomyopathy pedigree standing
- resolved
Thymopoietin (lamina-associated polypeptide 2) gene mutation associated with dilated cardiomyopathy.
Taylor MR, Slavov D, Gajewski A, Vlcek S, Ku L, Fain PR, Carniel E, Di Lenarda A, Sinagra G, Boucek MM, Cavanaugh J, Graw SL, Ruegg P, Feiger J, Zhu X, Ferguson DA, Bristow MR, Gotzmann J, Foisner R, Mestroni L, Familial Cardiomyopathy Registry Research Group
pmid 16247757
- preclinical
  Claim: Amino acid sequence of bovine thymopoietin II (49 residues) standing
- resolved
The amino acid sequence of thymopoietin II.
Schlesinger DH, Goldstein G
pmid 1171728
- preclinical
  Claim: A synthetic thymopoietin 32-36 pentapeptide carries the hormone's T-cell differentiating activity standing
- resolved
A synthetic pentapeptide with biological activity characteristic of the thymic hormone thymopoietin.
Goldstein G, Scheid MP, Boyse EA, Schlesinger DH, Van Wauwe J
pmid 451537

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.