Peptide Atlas · Salt form

Trifluoroacetate salt

Most synthetic peptides are made by solid-phase synthesis, whose cleavage and purification steps leave cationic peptides as trifluoroacetate salts.

preclinical

provisional
PubChem 6422
2 citations
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TFA salt

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- preclinical
  Claim: Elimination and exchange of the trifluoroacetate counter-ion from peptides standing
- resolved
Elimination and exchange of trifluoroacetate counter-ion from cationic peptides: a critical evaluation of different approaches.
Roux S, Zékri E, Rousseau B, Paternostre M, Cintrat JC, Fay N
pmid 18035848
- preclinical
  Claim: Consensus on analysis and exchange of TFA counterions in synthetic peptides standing
- resolved
Towards a Consensus for the Analysis and Exchange of TFA as a Counterion in Synthetic Peptides and Its Influence on Membrane Permeation.
Erckes V, Streuli A, Chamera Rendueles L, Krämer SD, Steuer C
pmid 40872554

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