Peptide Atlas · Cofactor

Adenosylcobalamin (Vitamin B12, coenzyme B12)

Adenosylcobalamin is one of the two coenzyme forms of vitamin B12 (cobalamin), one of the most structurally complex small molecules made in nature; its full biosynthesis from uroporphyrinogen III has been worked out.

emerging

provisional
PubChem 6474320
2 citations
0 discussions
0 followers
5'-deoxyadenosylcobalamin
AdoCbl
Cobamamide
Coenzyme B12
Dibencozide

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Adenosylcobalamin (Vitamin B12, coenzyme B12). Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Adenosylcobalamin given to a child with cblB methylmalonic acidaemia gave no sustained response	emerging	pmid 6434828
Review of the biosynthesis of adenosylcobalamin	preclinical	pmid 12195810

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.