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Peptide Atlas · Cofactor

Adenosylcobalamin (Vitamin B12, coenzyme B12)

Adenosylcobalamin is one of the two coenzyme forms of vitamin B12 (cobalamin), one of the most structurally complex small molecules made in nature; its full biosynthesis from uroporphyrinogen III has been worked out.

What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

    • emerging
      Claim: Adenosylcobalamin given to a child with cblB methylmalonic acidaemia gave no sustained response standing
    • resolved

    Treatment of the cbl B form of methylmalonic acidaemia with adenosylcobalamin.

    Batshaw ML, Thomas GH, Cohen SR, Matalon R, Mahoney MJ

    pmid 6434828

    • preclinical
      Claim: Review of the biosynthesis of adenosylcobalamin standing
    • resolved

    The biosynthesis of adenosylcobalamin (vitamin B12).

    Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC

    pmid 12195810

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.