PepJunkie Home of the Peptonauts
More

Peptide Atlas · Cofactor

Adenosylcobalamin (Vitamin B12, coenzyme B12)

Adenosylcobalamin is one of the two coenzyme forms of vitamin B12 (cobalamin), one of the most structurally complex small molecules made in nature; its full biosynthesis from uroporphyrinogen III has been worked out.

What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

  • created page created as 'Adenosylcobalamin (Vitamin B12, coenzyme B12)' with aliases Cobamamide, Dibencozide, AdoCbl, Coenzyme B12, 5'-deoxyadenosylcobalamin · 2026-09-27 12:04 · somebody
  • kind set kind set to cofactor: palette r2 · 2026-09-27 12:04 · somebody
  • fact added identity: PubChem CID 6474320: Coenzyme B12, C72H100CoN18O17P, 1579.6 g/mol. · 2026-09-27 12:04 · somebody
  • fact added identity: CAS registry number 13870-90-1. · 2026-09-27 12:04 · somebody
  • fact added summary: Adenosylcobalamin is one of the two coenzyme forms of vitamin B12 (cobalamin), one of the most structurally complex smal · 2026-09-27 12:04 · somebody
  • fact added mechanism: Adenosylcobalamin is the coenzyme of the mitochondrial enzyme methylmalonyl-CoA mutase; in a child with the cblB form of · 2026-09-27 12:04 · somebody
  • citation added pmid 12195810 cited as preclinical: Review of the biosynthesis of adenosylcobalamin · 2026-09-27 12:04 · somebody
  • citation added pmid 6434828 cited as emerging: Adenosylcobalamin given to a child with cblB methylmalonic acidaemia gave no sustained response · 2026-09-27 12:04 · somebody

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.