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Peptide Atlas · Excipient

Benzyl Alcohol

Benzyl alcohol is an antimicrobial preservative; it accelerated the aggregation and precipitation of recombinant interleukin-1 receptor antagonist by shifting the protein toward partially unfolded forms.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 3 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Benzyl Alcohol. Tier reflects study design, not enthusiasm.
ClaimTierSource
Fatal benzyl alcohol poisoning in a neonatal intensive care unit (Lancet 1982)establishedpmid 6123006
The gasping syndrome and benzyl alcohol poisoning (NEJM 1982)establishedpmid 7133084
Mechanism of benzyl alcohol-induced protein aggregationpreclinicalpmid 15514986

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.