Benzyl alcohol is an antimicrobial preservative; it accelerated the aggregation and precipitation of recombinant interleukin-1 receptor antagonist by shifting the protein toward partially unfolded forms.
fact added summary: Benzyl alcohol is an antimicrobial preservative; it accelerated the aggregation and precipitation of recombinant interle · 2026-09-27 04:00 · somebody
fact added history: In 1982 fatal benzyl alcohol poisoning was reported from a neonatal intensive care unit. · 2026-09-27 04:00 · somebody
fact added history: The same year, a gasping syndrome was described as benzyl alcohol poisoning. · 2026-09-27 04:00 · somebody
citation added pmid 15514986 cited as preclinical: Mechanism of benzyl alcohol-induced protein aggregation · 2026-09-27 04:00 · somebody
citation added pmid 7133084 cited as established: The gasping syndrome and benzyl alcohol poisoning (NEJM 1982) · 2026-09-27 04:00 · somebody
citation added pmid 6123006 cited as established: Fatal benzyl alcohol poisoning in a neonatal intensive care unit (Lancet 1982) · 2026-09-27 04:00 · somebody
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