Peptide Atlas · Peptide

GHK (free tripeptide, no copper)

GHK (glycyl-L-histidyl-L-lysine) is a human copper-binding tripeptide whose levels decline with age; it has been reported to support wound healing and tissue repair and to increase collagen and decorin.

preclinical

provisional
PubChem 73587
2 citations
0 discussions
0 followers
GHK basic
Glycyl-L-histidyl-L-lysine
NSC 379527
Tripeptide-1

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for GHK (free tripeptide, no copper). Tier reflects study design, not enthusiasm.
Claim	Tier	Source
GHK reverses an emphysema-associated gene-expression signature (Connectivity Map) and acts on fibroblasts	preclinical	pmid 22937864
GHK's reported biological actions and gene-expression effects relevant to the nervous system	preclinical	pmid 28212278

Unanswered questions

Most reports concern GHK bound to copper; which findings are specific to the free tripeptide? open

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.