GHK (glycyl-L-histidyl-L-lysine) is a human copper-binding tripeptide whose levels decline with age; it has been reported to support wound healing and tissue repair and to increase collagen and decorin.
preclinical — animal, cell or mechanistic work — not yet about people
every claim resolves to its source
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preclinical
Claim: GHK reverses an emphysema-associated gene-expression signature (Connectivity Map) and acts on fibroblastsstanding
resolved
A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK.
Campbell JD, McDonough JE, Zeskind JE, Hackett TL, Pechkovsky DV, Brandsma CA, Suzuki M, Gosselink JV, Liu G, Alekseyev YO, Xiao J, Zhang X, Hayashi S, Cooper JD, Timens W, Postma DS, Knight DA, Lenburg ME, Hogg JC, Spira A
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Negative findings
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