GHK (glycyl-L-histidyl-L-lysine) is a human copper-binding tripeptide whose levels decline with age; it has been reported to support wound healing and tissue repair and to increase collagen and decorin.
preclinical — animal, cell or mechanistic work — not yet about people
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created page created as 'GHK (free tripeptide, no copper)' with aliases Tripeptide-1, Glycyl-L-histidyl-L-lysine, GHK basic, NSC 379527 · 2026-09-27 12:04 · somebody
kind set kind set to peptide: palette r2 · 2026-09-27 12:04 · somebody
fact added summary: GHK (glycyl-L-histidyl-L-lysine) is a human copper-binding tripeptide whose levels decline with age; it has been reporte · 2026-09-27 12:04 · somebody
fact added mechanism: In a Connectivity Map analysis of lung tissue from smokers with COPD, GHK was identified as reversing the gene-expressio · 2026-09-27 12:04 · somebody
citation added pmid 28212278 cited as preclinical: GHK's reported biological actions and gene-expression effects relevant to the nervous system · 2026-09-27 12:04 · somebody
citation added pmid 22937864 cited as preclinical: GHK reverses an emphysema-associated gene-expression signature (Connectivity Map) and acts on fibrob · 2026-09-27 12:04 · somebody
question added Most reports concern GHK bound to copper; which findings are specific to the free tripeptide? · 2026-09-27 12:04 · somebody
Negative findings
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