Arginine is widely used in protein production as an aggregation suppressor rather than a protein stabilizer, acting by weakening protein-protein interactions.
fact added summary: Arginine is widely used in protein production as an aggregation suppressor rather than a protein stabilizer, acting by w · 2026-09-27 04:00 · somebody
fact added mechanism: It barely changed protein melting temperature but increased the reversibility of thermal melting and reduced aggregation · 2026-09-27 04:00 · somebody
citation added pmid 16522173 cited as preclinical: Review: why arginine is effective in suppressing aggregation · 2026-09-27 04:00 · somebody
citation added pmid 12705899 cited as preclinical: Arginine suppresses aggregation rather than facilitating refolding · 2026-09-27 04:00 · somebody
Negative findings
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