Peptide Atlas · Excipient

L-Arginine HCl

Arginine is widely used in protein production as an aggregation suppressor rather than a protein stabilizer, acting by weakening protein-protein interactions.

preclinical

provisional
PubChem 66250
2 citations
0 discussions
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Arginine
L-Arginine hydrochloride

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- preclinical
  Claim: Arginine suppresses aggregation rather than facilitating refolding standing
- resolved
The effects of arginine on refolding of aggregated proteins: not facilitate refolding, but suppress aggregation.
Arakawa T, Tsumoto K
pmid 12705899
- preclinical
  Claim: Review: why arginine is effective in suppressing aggregation standing
- resolved
Review: Why is arginine effective in suppressing aggregation?
Tsumoto K, Ejima D, Kita Y, Arakawa T
pmid 16522173

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Negative findings

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