Leuprorelin (leuprolide acetate) is a GnRH analogue that causes a brief initial rise in gonadotrophins and then, with continued use, pituitary desensitisation and suppressed sex hormones; it is used in advanced prostate cancer, endometriosis and central precocious puberty.
established — replicated in humans, or settled by a regulator
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created page created as 'Leuprolide (Leuprorelin)' with aliases Leuprolide acetate, Leuprorelin, Lupron, Eligard, D-Leu6-LHRH-NHEt · 2026-09-27 12:04 · somebody
kind set kind set to peptide: palette r2 · 2026-09-27 12:04 · somebody
fact added identity: CAS registry number 53714-56-0. · 2026-09-27 12:04 · somebody
fact added summary: Leuprorelin (leuprolide acetate) is a GnRH analogue that causes a brief initial rise in gonadotrophins and then, with co · 2026-09-27 12:04 · somebody
fact added summary: In the 48-week JASMITT trial in 199 men with spinal and bulbar muscular atrophy, leuprorelin did not significantly impro · 2026-09-27 12:04 · somebody
citation added pmid 7533699 cited as established: Review of leuprorelin's pharmacology and uses in sex-hormone-related disorders · 2026-09-27 12:04 · somebody
citation added pmid 20691641 cited as established: Leuprorelin missed its primary endpoint in spinal and bulbar muscular atrophy (JASMITT RCT) · 2026-09-27 12:04 · somebody
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