Peptide Atlas · Vitamin

Levoleucovorin / Folinic acid (calcium folinate, reduced folate B9)

Levoleucovorin is the active isomer of leucovorin (folinic acid); in gastrointestinal cancers treated with 5-fluorouracil, randomized trials found similar efficacy and tolerability with levoleucovorin and the racemic form.

established

provisional
PubChem 135500522
2 citations
0 discussions
0 followers
5-formyltetrahydrofolate
Calcium folinate
Citrovorum factor
Folinic acid
Leucovorin calcium
Levoleucovorin calcium

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: Meta-analysis: folate receptor autoantibodies and leucovorin treatment in autism standing
- resolved
Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis.
Rossignol DA, Frye RE
pmid 34834493
- established
  Claim: Levoleucovorin performs like racemic leucovorin with 5-FU (literature review) standing
- resolved
Is levoleucovorin an alternative to racemic leucovorin? A literature review.
Kovoor PA, Karim SM, Marshall JL
pmid 19822510

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Negative findings

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