fact added summary: Lidocaine is a local anaesthetic; its solutions are acidic and cause pain on infiltration into the skin. · 2026-09-27 04:00 · somebody
fact added history: In a randomized study of 100 patients, adding sodium bicarbonate to lidocaine significantly reduced pain during cannulat · 2026-09-27 04:00 · somebody
citation added pmid 16384767 cited as established: Buffered versus freshly mixed lidocaine: pain of infiltration · 2026-09-27 04:00 · somebody
citation added pmid 2174653 cited as established: pH adjustment and discomfort of intradermal lignocaine, randomized · 2026-09-27 04:00 · somebody
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