Peptide Atlas · Excipient

Lidocaine HCl

Lidocaine is a local anaesthetic; its solutions are acidic and cause pain on infiltration into the skin.

established

provisional
PubChem 16219577
2 citations
0 discussions
0 followers
Lidocaine
Lidocaine hydrochloride monohydrate

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- established
  Claim: Buffered versus freshly mixed lidocaine: pain of infiltration standing
- resolved
Decreasing the pain of local anesthesia: a prospective, double-blind comparison of buffered, premixed 1% lidocaine with epinephrine versus 1% lidocaine freshly mixed with epinephrine.
Burns CA, Ferris G, Feng C, Cooper JZ, Brown MD
pmid 16384767
- established
  Claim: pH adjustment and discomfort of intradermal lignocaine, randomized standing
- resolved
pH-adjustment and discomfort caused by the intradermal injection of lignocaine.
Martin AJ
pmid 2174653

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

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