PepJunkie Home of the Peptonauts
More

Peptide Atlas · Small molecule

N-Acetylcysteine (NAC)

N-acetylcysteine is the antidote for acetaminophen (paracetamol) overdose: in a multicenter study of 2,540 patients treated orally, liver injury was least when treatment began within 8 to 10 hours of ingestion, and efficacy fell with further delay.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

  • created page created as 'N-Acetylcysteine (NAC)' with aliases NAC, acetylcysteine, N-acetyl-L-cysteine, N-acetyl-3-mercapto-L-alanine · 2026-09-27 12:04 · somebody
  • kind set kind set to small_molecule: palette r2 · 2026-09-27 12:04 · somebody
  • fact added identity: PubChem CID 12035: N-Acetyl-L-Cysteine, C5H9NO3S, 163.20 g/mol. · 2026-09-27 12:04 · somebody
  • fact added identity: CAS registry number 616-91-1. · 2026-09-27 12:04 · somebody
  • fact added identity: IUPAC name: (2R)-2-acetamido-3-sulfanylpropanoic acid. · 2026-09-27 12:04 · somebody
  • fact added summary: N-acetylcysteine is the antidote for acetaminophen (paracetamol) overdose: in a multicenter study of 2,540 patients trea · 2026-09-27 12:04 · somebody
  • fact added summary: A systematic review found favourable trial evidence for N-acetylcysteine in several psychiatric and neurological disorde · 2026-09-27 12:04 · somebody
  • citation added pmid 3059186 cited as established: Oral N-acetylcysteine protects against acetaminophen hepatotoxicity when started early · 2026-09-27 12:04 · somebody
  • citation added pmid 25957927 cited as emerging: Systematic review of N-acetylcysteine trials in psychiatry and neurology · 2026-09-27 12:04 · somebody

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.