Pramlintide is a synthetic analogue of human amylin; in a 52-week trial in 651 people with type 1 diabetes, mealtime pramlintide added to insulin lowered HbA1c by 0.29-0.34% more than placebo, with a small weight loss and transient nausea.
fact added identity: CAS registry number 151126-32-8. · 2026-09-27 12:04 · somebody
fact added summary: Pramlintide is a synthetic analogue of human amylin; in a 52-week trial in 651 people with type 1 diabetes, mealtime pra · 2026-09-27 12:04 · somebody
fact added summary: In 656 insulin-treated people with type 2 diabetes, pramlintide 120 micrograms twice daily lowered HbA1c by about 0.6% o · 2026-09-27 12:04 · somebody
citation added pmid 15498087 cited as established: Pramlintide with insulin improved glycaemic and weight control in type 1 diabetes (52-week RCT) · 2026-09-27 12:04 · somebody
citation added pmid 12610038 cited as established: Pramlintide with insulin improved glycaemic and weight control in type 2 diabetes (52-week RCT) · 2026-09-27 12:04 · somebody
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