Peptide Atlas · Peptide

Pramlintide

Pramlintide is a synthetic analogue of human amylin; in a 52-week trial in 651 people with type 1 diabetes, mealtime pramlintide added to insulin lowered HbA1c by 0.29-0.34% more than placebo, with a small weight loss and transient nausea.

established

provisional
PubChem 70691388
2 citations
0 discussions
0 followers
AC137
Symlin
pramlintide acetate

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Pramlintide. Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Pramlintide with insulin improved glycaemic and weight control in type 2 diabetes (52-week RCT)	established	pmid 12610038
Pramlintide with insulin improved glycaemic and weight control in type 1 diabetes (52-week RCT)	established	pmid 15498087

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.