Peptide Atlas · Vitamin

Pyridoxine hydrochloride

High daily doses of pyridoxine (vitamin B6) caused ataxia and severe sensory neuropathy in seven adults, all of whom improved after stopping it.

established

provisional
PubChem 6019
2 citations
0 discussions
0 followers
Adermine hydrochloride
Pyridoxine HCl
Pyridoxol hydrochloride
Vitamin B6 hydrochloride

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Pyridoxine hydrochloride. Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Registry of 63 cases of pyridoxine-dependent and -responsive seizures	emerging	pmid 18762976
Sensory neuropathy from high-dose pyridoxine (case series)	established	pmid 6308447

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.